TY - JOUR U1 - Wissenschaftlicher Artikel A1 - Kar, Saradia A1 - Mai, Hans-Jörg A1 - Khalouf, Hadeel A1 - Ben Abdallah, Heithem A1 - Flachbart, Samantha A1 - Fink-Straube, Claudia A1 - Bräutigam, Andrea A1 - Xiong, Guosheng A1 - Shang, Lianguang A1 - Panda, Sanjib Kumar A1 - Bauer, Petra T1 - Comparative Transcriptomics of Lowland Rice Varieties Uncovers Novel Candidate Genes for Adaptive Iron Excess Tolerance JF - Plant and Cell Physiology N2 - Iron (Fe) toxicity is a major challenge for plant cultivation in acidic waterlogged soil environments, where lowland rice is a major staple food crop. Only few studies have addressed the molecular characterization of excess Fe tolerance in rice, and these highlight different mechanisms for Fe tolerance. Out of 16 lowland rice varieties, we identified a pair of contrasting lines, Fe-tolerant Lachit and -susceptible Hacha. The two lines differed in their physiological and morphological responses to excess Fe, including leaf growth, leaf rolling, reactive oxygen species generation and Fe and metal contents. These responses were likely due to genetic origin as they were mirrored by differential gene expression patterns, obtained through RNA sequencing, and corresponding gene ontology term enrichment in tolerant vs. susceptible lines. Thirty-five genes of the metal homeostasis category, mainly root expressed, showed differential transcriptomic profiles suggestive of an induced tolerance mechanism. Twenty-two out of these 35 metal homeostasis genes were present in selection sweep genomic regions, in breeding signatures, and/or differentiated during rice domestication. These findings suggest that Fe excess tolerance is an important trait in the domestication of lowland rice, and the identified genes may further serve to design the targeted Fe tolerance breeding of rice crops. Y1 - 2021 UN - https://nbn-resolving.org/urn:nbn:de:bsz:291:415-1304 U6 - https://doi.org/10.1093/pcp/pcab018 DO - https://doi.org/10.1093/pcp/pcab018 VL - 62 IS - 4 SP - 624 EP - 640 ER -