TY  - JOUR
U1  - Wissenschaftlicher Artikel
A1  - Harfoush, Shaza A.
A1  - Hannig, Matthias
A1  - Le, Duc Dung
A1  - Heck, Sebastian
A1  - Leitner, Maximilian
A1  - Omlor, Albert Joachim
A1  - Tavernaro, Isabella
A1  - Kraegeloh, Annette
A1  - Kautenburger, Ralf
A1  - Kickelbick, Guido
A1  - Beilhack, Andreas
A1  - Bischoff, Markus
A1  - Nguyen, Juliane
A1  - Sester, Martina
A1  - Bals, Robert
A1  - Dinh, Quoc Thai
T1  - High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice
JF  - Respiratory Research
N2  - Titanium dioxide nanoparticles (TiO2 NPs) have a wide range of applications in several industrial and biomedical domains. Based on the evidence, the workers exposed to inhaled nanosized TiO2 powder are more susceptible to the risks of developing respiratory diseases. Accordingly, this issue has increasingly attracted the researchers’ interest in understanding the consequences of TiO2 NPs exposure. Regarding this, the present study was conducted to analyze the local effects of TiO2 NPs on allergic airway inflammation and their uptake in a mouse model of ovalbumin (OVA)-induced allergic airway inflammation.
Y1  - 2020
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:291:415-3555
SN  - 1465-993X
SS  - 1465-993X
U6  - https://doi.org/10.1186/s12931-020-01386-0
DO  - https://doi.org/10.1186/s12931-020-01386-0
VL  - 21
IS  - 1
SP  - 168
S1  - 168
ER  -