TY  - JOUR
U1  - Zeitschriftenartikel, wissenschaftlich - nicht begutachtet (unreviewed)
A1  - Khan, Essak S.
A1  - Sankaran, Shrikrishnan
A1  - Paez, Julieta I.
A1  - Muth, Christina
A1  - Han, Mitchell K. L.
A1  - del Campo Bécares, Aránzazu
T1  - Photoactivatable Hsp47: A Tool to Control and Regulate Collagen Secretion & Assembly
T2  - ChemRxiv
N2  - Hsp47 is a chaperone protein with a fundamental role in the folding, stability and intracellular transport of procollagen triple helices. A light-responsive Hsp47 recombinant protein, engineered to control in situ the production and assembly of cellular collagen is here demonstrated. This novel light-driven tool enables unprecedented fundamental studies of collagen biosynthesis and associated diseases.
KW  - collagen
KW  - Hsp47
KW  - KDEL receptor mediated endocytosis
KW  - biological activity
KW  - photoactivation
Y1  - 2018
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:291:415-5336
U6  - https://doi.org/10.26434/chemrxiv.6964703.v3
DO  - https://doi.org/10.26434/chemrxiv.6964703.v3
SP  - 1
EP  - 32
ET  - Version 3
ER  -