High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice
- Titanium dioxide nanoparticles (TiO2 NPs) have a wide range of applications in several industrial and biomedical domains. Based on the evidence, the workers exposed to inhaled nanosized TiO2 powder are more susceptible to the risks of developing respiratory diseases. Accordingly, this issue has increasingly attracted the researchers’ interest in understanding the consequences of TiO2 NPs exposure. Regarding this, the present study was conducted to analyze the local effects of TiO2 NPs on allergic airway inflammation and their uptake in a mouse model of ovalbumin (OVA)-induced allergic airway inflammation.
Download full text files
Additional Services
Statistics
| Document Type: | Article |
|---|---|
| Author: | Shaza A. Harfoush, Matthias HannigORCiD, Duc Dung Le, Sebastian Heck, Maximilian Leitner, Albert Joachim Omlor, Isabella Tavernaro, Annette KraegelohORCiD, Ralf KautenburgerORCiD, Guido KickelbickORCiD, Andreas Beilhack, Markus BischoffORCiD, Juliane NguyenORCiD, Martina Sester, Robert BalsORCiD, Quoc Thai Dinh |
| URN: | urn:nbn:de:bsz:291:415-3555 |
| DOI: | https://doi.org/10.1186/s12931-020-01386-0 |
| ISSN: | 1465-993X |
| Parent Title (English): | Respiratory Research |
| Volume: | 21 |
| Issue: | 1 |
| Pagenumber: | 168 |
| Language: | English |
| Year of first Publication: | 2020 |
| Release Date: | 2022/11/18 |
| Impact: | 05.631 (2020) |
| Funding Information: | Stiftung Bergmannshilfswerks Luisenthal |
| Scientific Units: | Nano Cell Interactions |
| Open Access: | Open Access |
| Signature: | INM 2020/081 |
| Licence (German): |  Creative Commons - CC BY - Namensnennung 4.0 International |
