Liquid-Phase Electron Microscopy for Soft Matter Science and Biology
- Abstract Innovations in liquid-phase electron microscopy (LP-EM) have made it possible to perform experiments at the optimized conditions needed to examine soft matter. The main obstacle is conducting experiments in such a way that electron beam radiation can be used to obtain answers for scientific questions without changing the structure and (bio)chemical processes in the sample due to the influence of the radiation. By overcoming these experimental difficulties at least partially, LP-EM has evolved into a new microscopy method with nanometer spatial resolution and sub-second temporal resolution for analysis of soft matter in materials science and biology. Both experimental design and applications of LP-EM for soft matter materials science and biological research are reviewed, and a perspective of possible future directions is given.
| Document Type: | Article |
|---|---|
| Author: | Hanglong Wu, Heiner Friedrich, Joseph P. PattersonORCiD, Nico SommerdijkORCiD, Niels de JongeORCiD |
| URN: | urn:nbn:de:bsz:291:415-4956 |
| DOI: | https://doi.org/10.1002/adma.202001582 |
| ISSN: | 0935-9648 |
| Parent Title (English): | Advanced Materials |
| Volume: | 32 |
| Issue: | 25 |
| Pagenumber: | 2001582 |
| Language: | English |
| Year of first Publication: | 2020 |
| Release Date: | 2022/11/18 |
| Impact: | 30.849 (2020) |
| Funding Information: | H2020 Marie Sk łodowska-Curie Actions (676045) |
| Scientific Units: | Innovative Electron Microscopy |
| Open Access: | Open Access |
| Signature: | INM 2020/051 |
| Licence (German): |  Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International |
