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Liquid-Phase Electron Microscopy for Soft Matter Science and Biology

  • Abstract Innovations in liquid-phase electron microscopy (LP-EM) have made it possible to perform experiments at the optimized conditions needed to examine soft matter. The main obstacle is conducting experiments in such a way that electron beam radiation can be used to obtain answers for scientific questions without changing the structure and (bio)chemical processes in the sample due to the influence of the radiation. By overcoming these experimental difficulties at least partially, LP-EM has evolved into a new microscopy method with nanometer spatial resolution and sub-second temporal resolution for analysis of soft matter in materials science and biology. Both experimental design and applications of LP-EM for soft matter materials science and biological research are reviewed, and a perspective of possible future directions is given.

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Metadaten
Document Type:Article
Author:Hanglong Wu, Heiner Friedrich, Joseph P. Patterson, Nico SommerdijkORCiD, Niels de JongeORCiD
URN:urn:nbn:de:bsz:291:415-4956
DOI:https://doi.org/10.1002/adma.202001582
ISSN:0935-9648
Parent Title (English):Advanced Materials
Volume:32
Issue:25
Pagenumber:2001582
Language:English
Year of first Publication:2020
Release Date:2022/11/18
Impact:30.849 (2020)
Funding Information:H2020 Marie Sk Ĺ‚odowska-Curie Actions (676045)
Groups:Innovative Elektronenmikroskopie
Researchfields:Grenzflächenmaterialien
Open Access:Open Access
Signature:INM 2020/051
Licence (German):License LogoCreative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International