Thiol-methylsulfone-based Hydrogels for Cell Encapsulation: Reactivity Optimization of Aryl-methylsulfone Substrate for Fine-tunable Gelation Rate and Improved Stability
- We present novel thiol-methylsulfone hydrogels for cell encapsulation applications. The reactivity of the methylsulfonyl reactive partner has been optimized to improve the properties of the derived hydrogels for cell encapsulation.
Document Type: | Preprint |
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Author: | Julieta I. PaezORCiD, Adrián de Miguel-Jimenez, Rocío Valbuena Mendoza, Aditi Rathore, Minye Jin, Alisa Gläser, Samuel Pearson, Aránzazu del Campo BécaresORCiD |
URN: | urn:nbn:de:bsz:291:415-845 |
DOI: | https://doi.org/10.26434/chemrxiv.14115404.v1 |
Parent Title (English): | chemRxiv |
Language: | English |
Date of first Publication: | 2021/02/26 |
Release Date: | 2022/08/09 |
Tag: | PEG hydrogels; cell encapsulation; gel stability; thiol-arylmethylsulfone; water-based crosslinking reactions |
Funding Information: | Deutsche Forschungsgemeinschaft (DFG, Project no. 422041745); Deutscher Akademischer Austauschdienst (DAAD, Exchange Internship Program); European Union’s Horizon 2020 research and innovation programme under the FET PROACTIVE grant agreement no. 731957 (Mechano-Control) |
Groups: | Dynamische Biomaterialien |
Researchfields: | Biogrenzflächen |
DDC classes: | 500 Naturwissenschaften und Mathematik / 570 Biowissenschaften, Biologie |
Open Access: | Open Access |
Signature: | INM 2021/018_preprint |
Licence (German): | ![]() |